RNA, U6 small nuclear 58, pseudogene (RNU6-58P)

RNU6-58P, also referred to as "RNA, U6 small nuclear 58, pseudogene," is a pseudogene of a small nuclear RNA (snRNA) originally involved in the splicing of pre-mRNA as part of the spliceosome machinery[7][2]. Functional U6 snRNA is an essential and highly conserved component of the spliceosomal complex, crucial for catalyzing intron removal from pre-messenger RNA[5]. However, because RNU6-58P is annotated as a pseudogene, it is generally regarded as a non-functional genomic copy and does not contribute to snRNP-mediated catalysis or splicing[7][2]. Pseudogenes typically arise from duplication or retrotransposition events and lack coding or regulatory potential required for normal cellular roles. No evidence supports its use as a therapeutic target or biomarker, and there are no drugs known to interact with this gene. Supporting details: - This gene is listed as a pseudogene, meaning it is not expected to produce a functional RNA product and is not involved directly in any known biological or disease pathways[7][2]. - No alternative molecular functions, drug interactions, or disease roles are attributed to it. - It has standard identifiers such as HGNC:42548, NCBI Gene: 100873766, and Ensembl: ENSG00000252952[7][2]. Note: This entry refers specifically to a pseudogene rather than the functional U6 small nuclear RNA. Functional U6 snRNA is important in RNA processing and splicing, but the pseudogene copy RNU6-58P does not share these activities[5][7].

Other names

RNU6-58RNA, U6 small nuclear 58, pseudogene