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RNA, U6 small nuclear 64, pseudogene (RNU6-64P)
- Target
- RNU6-64P
- Molecular classification
- Other, non-coding RNA pseudogene, small nuclear RNA-derived pseudogene
01
Overview
RNA, U6 small nuclear 64, pseudogene" (RNU6-64P) is a *pseudogene* derived from the U6 small nuclear RNA (snRNA) gene family[4][7]. U6 snRNA is an essential uridine-rich non-coding RNA that participates in the spliceosome complex, catalyzing the removal of introns from pre-mRNA during mRNA splicing[1][5]. However, *pseudogenes* like RNU6-64P are non-functional genomic sequences that result from duplication or retrotransposition events involving U6 snRNA[4][7]. They do not encode a functional RNA product and typically do not participate in the splicing process or any other known cellular functions. The proliferation of U6-derived pseudogenes is considered a marker of retrotransposon activity and RNA retrotransposition dynamics within the genome[7]. There is no evidence for their use as therapeutic targets or for specific involvement in disease, nor are there currently any drugs interacting with or modulating RNU6-64P function.
- Other names
- RNU6-64RNU6-64P
02
Biological functions
Other (does not have an assigned biological function as a pseudogene, unlike functional U6 snRNA)
03
Disease associations
Other (no direct disease association for the pseudogene form, though lineage of parental U6 snRNA may have general importance in cell viability)
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