RNA, U6 small nuclear 641, pseudogene (RNU6-641P)

RNU6-641P is a *processed pseudogene*—a DNA segment that closely resembles the U6 small nuclear RNA gene, originally functional in RNA splicing as part of the spliceosome, but which now lacks a functional promoter or regulatory regions[6][4]. As a pseudogene, it is not transcribed or translated and does not encode functional protein or RNA. U6 snRNA itself is essential for pre-mRNA splicing in the nucleus, but pseudogenes such as RNU6-641P accumulate in the genome, typically as a result of retrotransposition[6][1]. These sequences are common backups found in vertebrate genomes, reflecting evolutionary history rather than active biological function[5][6][4]. There is no evidence that RNU6-641P or similar U6 pseudogenes are involved in disease, can serve as therapeutic targets, interact with drugs, act as biomarkers, or pose safety concerns. The listing is considered incorrect in the context of drug, therapeutic, or receptor target databases, as pseudogenes like RNU6-641P are not considered actionable molecular targets or functional biomolecules[6][4].

Other names

RNU6-641PRNA, U6 small nuclear 641, pseudogene