RNA, U6 small nuclear 649, pseudogene (RNU6-649P)

RNU6-649P is a pseudogene encoding a non-functional RNA sequence with homology to U6 small nuclear RNA (U6 snRNA), a highly conserved component of the spliceosome in eukaryotic cells. U6 snRNA is normally required for pre-mRNA splicing by coordinating the catalytic core of the spliceosome, but pseudogenes like RNU6-649P generally do not produce a functional product and are not involved in splicing or any biological process[3][5][6]. Sequencing data confirm that human genomes contain many pseudogene copies of U6 snRNA, such as RNU6-649P, which are believed to result from evolutionary duplications and insertions and lack evidence of expression or participation in cellular functions[5]. The RNU6-649P locus is annotated as a non-coding RNA pseudogene, and no experimental data supports a role in molecular function, biological process, or human disease[4][6]. RNU6-649P is not considered a therapeutic target, nor is it implicated in pathology or used as a biomarker or drug target.

Other names

RNU6-649PU6 snRNA pseudogene 649U6 small nuclear RNA pseudogene 649U6(4.8S) RNA pseudogene 649

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