Target intelligence / Profile preview

RNA, U6 small nuclear 65, pseudogene (RNU6-65P)

Target
RNU6-65P
Molecular classification
Other (pseudogene, noncoding RNA)
01

Overview

RNA, U6 small nuclear 65, pseudogene (RNU6-65P) is a human pseudogene derived from the U6 small nuclear RNA gene. U6 snRNA itself is a highly conserved, uridine-rich noncoding RNA that forms a key part of the spliceosome involved in intron removal from pre-mRNAs, but pseudogenes like RNU6-65P are thought to be non-functional remnants of gene duplication or retrotransposition events and do not code for functional RNA or protein[1][5]. RNU6-65P is annotated based on sequence similarity to functional U6 snRNA but lacks evidence for expression or functional contribution to splicing or disease. Pseudogenes such as RNU6-65P may sometimes have regulatory roles or produce noncoding RNAs, but there is currently no evidence or clinical implication for this specific locus[1][5].

Other names
RNU6-65RNU6-65P
02

Mechanism of action

None (as no drugs target this pseudogene)

03

Biological functions

None assigned specifically for RNU6-65P; functional U6 snRNA participates in nuclear pre-mRNA splicing, but pseudogenes like RNU6-65P lack evidence for a biological function
04

Disease associations

None described for the pseudogene RNU6-65P; (Note: functional U6 snRNA is essential for splicing, and disruption of snRNA components can underlie disease, but not for pseudogenes like RNU6-65P)
05

Safety considerations

None (there are no described safety concerns or therapeutic challenges for targeting this pseudogene)
06

Interacting drugs

None (no drugs are known to interact with this pseudogene)
07

Biomarkers

None assigned (this pseudogene is not established as a biomarker for patient selection or monitoring)

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