RNA, U6 small nuclear 702, pseudogene (RNU6-702P)

**RNA, U6 small nuclear 702, pseudogene** (RNU6-702P) is a human pseudogene related to the U6 small nuclear RNA (snRNA) family. U6 snRNA plays a central role in *pre-mRNA splicing* as an essential component of the spliceosome; however, RNU6-702P is a non-functional *pseudogene* copy of this RNA family and does not encode an active molecule involved in splicing[1][3][5]. Pseudogenes like RNU6-702P generally contain sequence similarities to their functional counterparts but have accumulated disabling mutations that prevent them from participating in canonical biological processes[2][4]. While some pseudogenes can have regulatory effects or serve as raw material for evolutionary innovation, most—including RNU6-702P—are considered "genomic fossils" without confirmed function or therapeutic relevance[2][4][5]. There is no evidence that RNU6-702P interacts with drugs, serves as a biomarker, or is used therapeutically. Key context: - The designation "pseudogene" indicates RNU6-702P is generally *not a protein/RNA drug target*, nor does it function in cell signaling, metabolism, or other classical "targetable" biology[2][4]. - Many U6-related pseudogenes are dispersed throughout vertebrate genomes as a result of retroposition or gene duplication[1][5]. - Functional U6 snRNA is essential for life; pseudogenes such as RNU6-702P lack this function[1][5]. - Some pseudogenes, in rare cases, may acquire new (regulatory) functions; there is no evidence this applies to RNU6-702P[2][4][5].

Other names

RNU6-702PU6 snRNA pseudogeneU6 small nuclear RNA pseudogene