RNA, U6 small nuclear 73, pseudogene (RNU6-73P)

RNA, U6 small nuclear 73, pseudogene (RNU6-73P), also known as RNU6-73, RNU6-73P, is a **pseudogene derived from the U6 small nuclear RNA (snRNA)** family[3][5]. Its sequence is modeled after the functional U6 snRNA but is not believed to produce a functional RNA product. The **RNU6-73P gene** is a **pseudogene** related to *human U6 small nuclear RNA (snRNA)*, a component of the spliceosome, which is essential for pre-mRNA splicing in eukaryotic cells[3][2]. The pseudogene itself, RNU6-73P, is a non-functional genetic sequence likely generated by retrotransposition events, where copies of U6 snRNA were inserted into new genomic locations but are not transcribed or involved in cellular processes[5][1]. The existence of pseudogenes such as RNU6-73P reflects the *evolutionary importance* of the U6 snRNA gene, but there is no evidence RNU6-73P encodes protein or functional RNA, nor is it involved in disease or targeted therapeutics[3][5]. The **functional U6 snRNA is critical for spliceosome formation and nuclear pre-mRNA splicing**[2][3]. However, **RNU6-73P does not encode a functional snRNA** and is *not implicated* in splicing, cellular signaling, or human disease. Its presence primarily serves as a marker of past genomic retrotransposition activity[5]. Summary: RNU6-73P is a **pseudogene** of U6 snRNA, with *no known functional, therapeutic, or disease relevance*. It is not a valid drug target, and its nomenclature often causes confusion when mistaken for functional spliceosome-associated snRNAs[5].

Other names

RNU6-73PRNU6-73RNA, U6 Small Nuclear 73, Pseudogene

None. No drugs act through this pseudogene.