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Target intelligence / Profile preview
RNA, U6 small nuclear 757, pseudogene (RNU6-757P)
- Target
- RNU6-757P
- Molecular classification
- Other (Pseudogene), Small nuclear RNA pseudogene
01
Overview
RNU6-757P encodes a pseudogene with high sequence similarity to U6 small nuclear RNA, a non-coding RNA integral to spliceosomal function in eukaryotic pre-mRNA splicing[1][4][5]. This particular locus (757) does not produce a functional RNA or protein; it is one of many U6-derived pseudogenes present in the human genome as the result of retrotranspositional or duplicative events[4][7]. These pseudogenes are markers of genetic retrotransposition dynamics and have no documented biological activity or clinical significance[4][7]. Key Points: U6 snRNA is essential to spliceosome function, but *RNU6-757P* is a non-functional pseudogene, not implicated in canonical splicing or any known human diseases, and not pursued as a therapeutic target[3][4][5][7]. Such pseudogenes may provide evolutionary insight but lack druggability or direct biomedical relevance. If you require information on the functional **U6 small nuclear RNA**, refer instead to the parent gene (U6 snRNA), not a pseudogene variant like RNU6-757P[3][5][4].
- Other names
- RNU6-757P
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