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RNU6-783P (RNA, U6 small nuclear 783, pseudogene) is a **pseudogene** derived from U6 small nuclear RNA (snRNA), which is a component of the spliceosome used in pre-mRNA splicing in eukaryotes[1][3]. Unlike functional U6 snRNA, a **pseudogene** such as RNU6-783P does not produce a functional RNA product because it has accumulated mutations preventing normal processing or function[2][3]. These pseudogenes typically arise through retrotransposition—often mediated by LINE elements—and serve as genomic remnants of active U6 snRNA genes[3]. Pseudogenes of snRNAs like U6 are numerous in vertebrate genomes but have no direct role in RNA processing, biological function, or disease. They are not considered therapeutic targets, do not interact with drugs, and are not used as biomarkers[2][3].
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