RNA, U6 small nuclear 803, pseudogene (RNU6-803P)

RNU6-803P is a human pseudogene that is classified as a non-coding RNA and is annotated as "RNA, U6 small nuclear 803, pseudogene"[4][5]. It shows sequence similarity to the highly conserved U6 small nuclear RNA (U6 snRNA), an essential component of the spliceosome involved in pre-mRNA splicing[1][3]. However, as a pseudogene, RNU6-803P does not produce a functional RNA molecule or protein and is not considered to have a direct biological function. Pseudogenes like RNU6-803P may be remnants of gene duplication or retrotransposition events and, although rarely, some pseudogenes have been shown to regulate the expression of their parental gene or participate in cellular regulatory networks via transcript interactions, but there is no evidence supporting such a role for RNU6-803P specifically[2][5]. It is not recognized as a therapeutic target. Supporting details: - **Genomic context:** Located on chromosome 19 (reverse strand, 53,719,064-53,719,165)[4]. - **Functional note:** Unlike true U6 snRNA, which is vital for spliceosomal function, pseudogenes like RNU6-803P are generally non-functional "backup" or relic sequences, though some pseudogenes elsewhere in the genome may act as regulatory RNAs[1][2][3]. - **Target status:** It is not a drug, receptor, transporter, or enzyme target. - **No established therapeutic or biomarker roles:** Not associated with specific drugs, biomarker uses, or safety liabilities[4][5]. Summary: RNU6-803P is a pseudogene resembling U6 small nuclear RNA, with no protein product, biological function, or role as a therapeutic target.

Other names

RNU6-803P