RNA, U6 small nuclear 891, pseudogene (RNU6-891P)

RNA, U6 small nuclear 891, pseudogene (RNU6-891P) is a non-coding RNA gene classified as a pseudogene, located on chromosome 4 in the human genome[1][3][5][7]. It is named for its sequence similarity to the U6 small nuclear RNA (snRNA), which is a vital component of the spliceosome involved in pre-mRNA splicing in eukaryotic cells[6]. However, as a pseudogene, RNU6-891P is generally considered non-functional and does not produce a functional RNA or protein product[7]. There is no evidence supporting a role for RNU6-891P as a therapeutic target, and it is not known to interact with drugs, serve as a biomarker, or play a role in disease. Context and Supporting Details: - RNU6-891P is recognized by nomenclature authorities (HGNC:47854) as a pseudogene related to U6 snRNA[5]. - U6 snRNA proper is a small nuclear RNA essential for splicing, but pseudogenes like RNU6-891P arise from gene duplication or retrotransposition events and have lost their original function[6][7]. - No biological or disease functions, known drug interactions, or roles as a biomarker are reported for this locus in reviewed genomic resources[1][5][7].

Other names

RNU6-891P