RNA, U6 small nuclear 918, pseudogene (RNU6-918P)

RNA, U6 small nuclear 918, pseudogene (RNU6-918P) is classified as a **pseudogene** of the U6 small nuclear RNA (snRNA) gene family in Homo sapiens, localized at cytogenetic region 9q22.33[1][3][9][12]. Pseudogenes like RNU6-918P are DNA sequences that *resemble functional genes* but are typically non-functional due to mutations or lack of necessary regulatory elements[4][6]. U6 snRNA itself is an essential component of the spliceosome, participating in pre-mRNA splicing, but pseudogenes do not normally produce functional RNA or protein[4]. Most snRNA pseudogenes, including those related to U6, are formed through L1/L1-like retrotransposition events[4][8]. There is no evidence that RNU6-918P is expressed or yields any functional products, and it is not considered a therapeutic target, receptor, or signaling molecule[3][7][12]. While some pseudogenes may act as regulators in certain contexts (e.g., as RNAs affecting gene expression or as disease markers), there is no published evidence for RNU6-918P having such a role[6][10]. Thus, its main interest is as a genomic marker for evolutionary and retrotransposition studies, not as a therapeutic or diagnostic target[4][8].

Other names

RNU6-918P