RNA, U6 small nuclear 933, pseudogene (RNU6-933P)

RNU6-933P (RNA, U6 small nuclear 933, pseudogene) is a non-coding RNA pseudogene located on chromosome 11 ([Ensembl: ENSG00000207153][2]). It is derived from the highly conserved U6 small nuclear RNA gene, a critical component of the spliceosomal machinery required for pre-mRNA splicing[1][5]. Unlike the canonical U6 snRNA, RNU6-933P is a defective copy that does not encode a functional RNA and thus does not participate directly in spliceosome assembly or catalysis. Such pseudogenes are formed by retrotransposition or gene duplication events and typically accumulate mutations that render them non-functional[4][7]. While most pseudogenes were historically considered "junk DNA," emerging evidence suggests some may influence gene regulation or act as competitive endogenous RNAs, though this is not specifically described for RNU6-933P[4][6]. It does not serve as a receptor, enzyme, transporter, or transcription factor, and there is no current evidence for direct roles in disease, drug interactions, or utility as a biomarker. Overall, RNU6-933P is best classified as a genomic pseudogene from the U6 small nuclear RNA family, without known direct functional or therapeutic implications.

Other names

RNU6-933PU6-933P

None (no drugs target this molecule)