RNA, U7 small nuclear 120 pseudogene (RNU7-120P)

**RNA, U7 small nuclear 120 pseudogene (RNU7-120P) is a pseudogene related to U7 small nuclear RNA (U7 snRNA), a non-coding RNA that is essential for the 3' end processing of replication-dependent histone pre-mRNAs[1][6][8].** However, *RNU7-120P* itself is a pseudogene and not a protein-coding gene or an active non-coding RNA. Pseudogenes like RNU7-120P are genomic DNA sequences similar to normal genes but are typically nonfunctional due to accumulated mutations or incomplete gene structure[8]. Whereas the canonical U7 snRNA is a validated, functional component of the U7 snRNP complex essential for histone mRNA maturation, the pseudogene variant (like RNU7-120P) is generally non-expressed, nonfunctional, and not considered a biological target or implicated in therapeutic intervention. **Additional detail:** - The functional U7 small nuclear RNA (not the pseudogene) is involved in the processing of the 3′ stem-loop of histone pre-mRNA but RNU7 pseudogenes, including RNU7-120P, are “presumed to be unexpressed” and have no known biological or pathological roles[8]. - There are multiple pseudogenes related to the U7 snRNA gene in the human genome, none of which are reported as functional or used as clinical biomarkers, therapeutic targets, or direct disease causes[8]. - If you are looking for information about the functional molecule, search for “U7 small nuclear RNA” rather than “RNU7-120P”[1][6][8]. **Summary:** RNU7-120P is a **nonfunctional pseudogene** for U7 snRNA, not a therapeutic or biomarker target. There is nothing known to be biologically or pharmacologically relevant about this pseudogene. It should not be considered a molecular target or gene of interest for drug discovery or biology applications[1][6][8].

Other names

U7 small nuclear RNA 120 pseudogeneRNU7-120P