Target intelligence / Profile preview

RNA, U7 small nuclear 187 pseudogene (RNU7-187P)

Target
RNU7-187P
Molecular classification
Pseudogene, Non-coding RNA
01

Overview

RNA, U7 small nuclear 187 pseudogene (RNU7-187P) is classified as a pseudogene in the human genome[7][11][5]. It shares sequence similarity with the functional U7 small nuclear RNA (snRNA) genes, which are components of the U7 small nuclear ribonucleoprotein (snRNP) complex involved in histone pre-mRNA 3′ end processing[2][3]. Pseudogenes like RNU7-187P are generally non-coding and do not produce functional snRNA or protein products; they are considered evolutionary remnants and are not believed to have direct biological or therapeutic roles[6][7]. RNU7-187P does not act as a therapeutic target, has no described molecular interactions or therapeutic ligands, and has no well-established roles as a biomarker or source of safety concern. It is distinct from functional U7 snRNA genes, which can be relevant in certain genetic and neurological disorders due to their role in histone mRNA maturation, but RNU7-187P itself is not implicated in such processes or diseases[7][2][3].

Other names
RNU7-187P
02

Biological functions

Other (No direct biological function; pseudogene of U7 small nuclear RNA)
03

Disease associations

Other (No established disease association; functional U7 snRNA genes, but not pseudogenes, are noted in histone mRNA processing and rare genetic disorders[3][2])

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