RNA, U7 small nuclear 197 pseudogene (RNU7-197P)

RNA, U7 small nuclear 197 pseudogene (RNU7-197P) is a pseudogene copy of the U7 small nuclear RNA gene, annotated in the human genome. Unlike functional U7 snRNA, which is essential for the 3' end processing of replication-dependent histone pre-mRNA, this pseudogene does not produce a functional RNA or protein product and is not associated with therapeutic modulation, disease, or endogenous physiological processes[1][5]. Key context: - The functional U7 snRNA gene (e.g., RNU7-1) is required in histone pre-mRNA processing and its disruption is associated with Aicardi-Goutières syndrome, but these functions and disease links do not extend to RNU7-197P, which is an inactive pseudogene[2][3][4][5]. - There is no evidence that RNU7-197P is expressed, involved in any pathway, or targeted by any current therapeutics[1]. Summary: RNU7-197P is an annotated pseudogene, not an active biological or therapeutic target. Information about the U7 small nuclear RNA system applies only to the "functional" U7 RNA genes and not to this pseudogene copy[1][5].

Other names

RNU7-197PRNA, U7 small nuclear 197 pseudogene

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