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RNA, U7 small nuclear 87 pseudogene (RNU7-87P) is a pseudogene in the human genome, annotated under NCBI Gene ID 100873842[8]. It is related to—but distinct from—the functional U7 small nuclear RNA (snRNA) gene, which encodes a small nuclear RNA component of the U7 snRNP complex. The U7 snRNA is critical for histone pre-mRNA 3' end processing[6]. RNU7-87P, as a pseudogene, does not encode a functional RNA and has no known biological activity, disease associations, or drug interactions. It is catalogued primarily for genome annotation completeness, rather than its direct biological or clinical relevance[1][7][8]. Summary of Key Points: - RNU7-87P is a pseudogene, not a protein-coding or functional snRNA gene[1][7][8]. - No evidence supports a role in disease, biomarker utility, or relevance as a therapeutic target. - Its functional counterpart, U7 snRNA, is a component of the machinery for processing histone pre-mRNA, but this specific pseudogene is biologically inactive in humans[6].
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