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Target intelligence / Profile preview
RNA polymerase II subunit J4 (pseudogene) (POLR2J4)
- Target
- POLR2J4
- Molecular classification
- Other, Pseudogene
01
Overview
RNA polymerase II subunit J4 (POLR2J4) is a pseudogene, not a protein-coding gene. It shares high sequence similarity with protein-coding genes (such as POLR2J, which encodes the RPB11 subunit of RNA polymerase II)[7][2][6]. Unlike its protein-coding counterparts, POLR2J4 does not encode a functional subunit of RNA polymerase II. Pseudogenes are generally classified as non-functional copies or remnants of genes that have lost their coding capability due to mutations[7][8]. While their main biological role may involve regulation of gene expression via RNA-based mechanisms, there is currently no evidence for direct protein function or involvement in human disease for POLR2J4. It does not serve as a therapeutic target, nor is it associated with drug interactions, biomarker utility, or safety concerns.
- Other names
- RASA4PRASA4CPRPB11-phiPolymerase (RNA) II (DNA directed) polypeptide J4, pseudogenePolymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa pseudogeneRNA polymerase II subunit J4, pseudogenePolymerase (RNA) II subunit J4, pseudogeneMGC13098
02
Mechanism of action
None
03
Biological functions
Other
04
Disease associations
Other
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