Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B)
- Target
- PDE6B
- Molecular classification
- Enzyme, Phosphodiesterase
01
Overview
PDE6B is the beta subunit of the rod cGMP-specific 3',5'-cyclic phosphodiesterase enzyme complex. This protein is essential for normal visual signal transduction in rod photoreceptor cells. The PDE6 complex hydrolyzes cyclic guanosine monophosphate (cGMP), a key second messenger in phototransduction. Mutations in *PDE6B* are linked to inherited retinal degenerative diseases such as retinitis pigmentosa and congenital stationary night blindness.
- Other names
- Phosphodiesterase 6BRod cGMP-PDE βGMP-PDEbetaRP40CSNB3
02
Mechanism of action
N/A
03
Biological functions
Signal transductionHydrolysis of cGMP in phototransduction
04
Disease associations
Retinitis pigmentosaCongenital stationary night blindness
Beyond the preview
Go deeper on Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B).