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Target intelligence / Profile preview
SARS-CoV-2-infected cell (via multiple viral peptides)
- Molecular classification
- Cell
01
Overview
A "SARS-CoV-2-infected cell" targeted via "multiple viral peptides" refers broadly to any human host cell presenting one or more antigenic fragments derived from various regions of the coronavirus genome/proteome after infection. Such identification enables both natural immune surveillance and engineered diagnostic/therapeutic interventions leveraging this multi-peptide display characteristic of active infection.
- Other names
- SARS-CoV-2 infected host cellCOVID-19 infected cellVirus-infected cell
02
Biological functions
Viral replicationAntigen presentationImmune evasionCell death
03
Disease associations
COVID-19 pathogenesisViral reservoir
04
Safety considerations
Off-target effects of immune-targeting therapiesPotential for cytokine storm
05
Biomarkers
Viral peptides presented on MHC-IViral peptides presented on MHC-II
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