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Target intelligence / Profile preview
Sialic acid binding Ig-like lectin 18, pseudogene (SIGLEC18P)
- Target
- SIGLEC18P
- Molecular classification
- Pseudogene, Immunoglobulin superfamily (I-type lectin, Siglec family)
01
Overview
Sialic acid binding Ig-like lectin 18, pseudogene (SIGLEC18P) is a human pseudogene belonging to the Siglec (sialic acid-binding immunoglobulin-like lectin) family. Unlike other Siglec genes that encode glycan-recognizing immune modulatory proteins, SIGLEC18P does not produce a functional protein product due to disabling mutations in its coding sequence. Siglec pseudogenes, including SIGLEC18P, are remnants of once-functional immune regulators that have lost protein-coding capacity in humans, although homologous genes in other primates may still be active. SIGLEC18P is not considered a valid target for therapeutic intervention or pharmacological modulation.
- Other names
- SIGLECP1
02
Mechanism of action
Not applicable (no protein product)
03
Biological functions
None known in humans (no functional protein product)In primates, its orthologs are part of the Siglec family, which generally modulate immune responses, but this human gene is inactivated
04
Disease associations
None established (no functional protein produced in humans)
05
Safety considerations
None (not a functional target)
06
Interacting drugs
None (no functional protein target is expressed)
07
Biomarkers
None known (not expressed as a protein in humans)
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