Target intelligence / Profile preview

Skeletal Muscle Cell (Autologous)

Molecular classification
Cell, Muscle cell, Somatic cell
01

Overview

An autologous skeletal muscle cell refers to a muscle cell derived from an individual's own skeletal muscle tissue. These cells are typically harvested via biopsy, expanded or manipulated ex vivo, and then reintroduced into the same individual for therapeutic purposes. This approach minimizes immune rejection and is used in regenerative medicine, disease modeling, and tissue engineering.

Other names
Autologous skeletal myoblastAutologous muscle-derived cell
02

Biological functions

Muscle contractionVoluntary movementTissue regenerationCell fusionDifferentiation
03

Disease associations

Muscular dystrophyMuscle atrophyGastrointestinal repair (muscle related)Cardiac repair (muscle related)
04

Safety considerations

Limited engraftmentVariable therapeutic efficacyPotential for fibrosisHeterogeneity of cell populationTumorigenesis potential (though considered low for autologous cells)
05

Biomarkers

Pax7Pax3Myf5M-cadherinc-Metα7-integrinCD34Syndecan 3/4CXCR4

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