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Skin moisture retention (emollient effect)

Molecular classification: Other

Overview

Skin moisture retention (emollient effect) refers to the physiological process and mechanisms by which emollients help maintain or increase water content in the skin, primarily through forming a protective barrier that reduces water loss. Emollients work by filling gaps between desiccated skin cells, forming an occlusive film to trap water, and reducing transepidermal water loss (TEWL).

Other names: Emollient effectCutaneous hydrationTransepidermal water loss (TEWL) reductionEpidermal barrier function

Mechanism of action

Occlusion; humectancy; lipid replenishment

Biological functions

Maintains cutaneous hydrationRestores epidermal barrierReduces transepidermal water loss (TEWL)Skin softening

Disease associations

Eczema/atopic dermatitisPsoriasisDry skinSensitive skin

Interacting drugs

Petrolatum

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