Small ribosomal subunit protein mS39, mitochondrial (PTCD3)

Small ribosomal subunit protein mS39, mitochondrial (PTCD3) is a mitochondrial RNA-binding protein that is a component of the mitochondrial small ribosomal subunit, playing a crucial role in mitochondrial translation by binding rRNA and contributing to the assembly and function of the mitochondrial ribosome. Mutations in PTCD3 have been associated with combined oxidative phosphorylation deficiency 51, implicating its importance in mitochondrial respiratory chain function[1][2][7][8]. Notes: - PTCD3 is not a typical therapeutic target such as a receptor, enzyme, transporter, or transcription factor, but rather a structural/functional ribosomal protein essential for mitochondrial gene expression and respiratory function[1][7][8]. - There are no known drugs or small molecules directly targeting PTCD3; thus, no mechanisms of action, biomarkers, or safety concerns directly related to therapeutics are reported for this molecule. - Aliases provided here are based on common entries in gene/protein databases and literature[1][8].

Other names

Pentatricopeptide repeat domain 3MRPS39TRG15MRP-S39TRG-15FLJ20758DKFZp666K071mS3928S ribosomal protein S39, mitochondrialPentatricopeptide repeat domain-containing protein 3, mitochondrialTransformation-related gene 15 proteinCOXPD51