SPATA31 subfamily B member 1, pseudogene (SPATA31B1P)

SPATA31 subfamily B member 1, pseudogene (SPATA31B1P) is a non-protein-coding pseudogene in humans, identified with several aliases. It is part of the segmentally duplicated SPATA31 gene family, which has roles in DNA repair and aging based on other functional family members, but the pseudogene itself lacks protein-coding capacity and is not directly involved in these functions. Pseudogenes resemble functional genes but contain mutations or sequence changes that prevent normal transcription and translation, and thus cannot produce a functional protein[2][3][4][6]. Pseudogenes like SPATA31B1P can complicate genetic studies and may have regulatory or evolutionary significance, but there is no evidence for direct therapeutic targeting or disease involvement for SPATA31B1P[4][6]. ESSENTIAL NOTES: SPATA31B1P is a pseudogene. It is structurally similar to functional gene family members (e.g., SPATA31A1), but by definition, it cannot encode a functional protein[2][3][4][6]. Pseudogenes are not considered therapeutic targets, as they lack protein product and direct disease association [4][6]. Other functional SPATA31 genes (not SPATA31B1P) have roles in DNA repair, aging, and potentially UV damage response, but these do not apply to SPATA31B1P itself[1]. Using SPATA31B1P as a therapeutic target is incorrect; the entry is included here for clarity per your instructions.

Other names

bA388B24.2C9orf36BFAM75BSPATA31B1SPATA31B1P