SPATA31 subfamily D member 5, pseudogene (SPATA31D5P)

SPATA31 subfamily D member 5, pseudogene (SPATA31D5P) is a human pseudogene located on chromosome 9q21[3]. It is part of the SPATA31 gene family, which is thought to be involved in spermatogenesis. As a pseudogene, SPATA31D5P does not encode a functional protein[1][2], but its transcript may act as a regulator of gene expression. Recent research shows that some pseudogenes, including SPATA31D5P, are significantly deregulated in cancer, particularly head and neck cancer, where changes in expression levels correlate with patient prognosis and relapse risk. These associations likely reflect a broader role for pseudogene transcripts in regulating pathways such as cell proliferation, stress response, cell death, immune signaling, and Wnt signaling[4]. However, there is no evidence that SPATA31D5P encodes a therapeutic target (such as receptor, enzyme, transporter, or ion channel), nor are there any known drugs or direct mechanisms of action associated with it. **Note:** Several gene and protein function descriptions for Varp found in the search results[5] are related to a different gene/protein, not to SPATA31D5P, and should be disregarded for this entry. SPATA31D5P is best classified as a cancer-associated pseudogene transcript, not a protein-coding or druggable target.

Other names

FAM75D5FAM75D5PFAM75-like protein FLJ46321 pseudogenefamily with sequence similarity 75, member D5, pseudogeneSPATA31D5P