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Spleen (traditional Chinese medicine) (null)
- Target
- null
- Molecular classification
- Other
01
Overview
The Spleen in traditional Chinese medicine (TCM) is a theoretical functional system responsible for the extraction, transformation, and distribution of nutrients and fluids derived from food, supporting the formation of blood and Qi, nourishing the muscles, and maintaining fluid balance in the body. It is associated with the Earth element, pairs with the Stomach, and governs aspects of mental activity and emotional balance. The TCM Spleen is not the same as the anatomical spleen, nor a single molecular entity, but rather an abstract network used to diagnose and treat imbalances in TCM practice through dietary therapy, herbal medicine, and acupuncture
- Other names
- Spleen (TCM)Pi (脾, pí)Spleen system (TCM)Spleen zang
02
Mechanism of action
Support Spleen function by enhancing "transportation and transformation" or "tonifying" through herbal compounds, dietary therapy, or acupuncture, as per TCM theory—not molecular actions in the Western biomedical sense
03
Biological functions
Transportation and transformation of food and fluidsProduction of Qi and bloodRegulation of fluid metabolismControl of blood within vesselsNourishment of muscles and limbsInfluence on intellect and mental function (Yi, 意)Immune function in a holistic, non-biochemical sense
04
Disease associations
Spleen deficiency syndromeDigestive disorders (as defined by TCM)Water/dampness retentionFatigue and muscle weaknessBlood disorders (as per TCM)Emotional imbalances (especially worry/anxiety)
05
Safety considerations
Misinterpretation of TCM Spleen as anatomical spleen may mislead diagnosis or therapy in biomedical contextsHerbal formulas used for "Spleen deficiency" may have pharmacologic effects or interactions, but these are not standardized or directly related to a molecular target
06
Interacting drugs
Classical Chinese herbal formulas that "tonify Spleen" (e.g. Si Jun Zi Tang, Bu Zhong Yi Qi Tang)
1 more in the full profile.
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