T, brachyury homolog pseudogene

The "T, brachyury homolog pseudogene" (ENSG00000250079, also known as LOC100533667) is annotated as a *pseudogene* in the human genome, meaning that it is a genomic sequence related to the BRACHYURY (T, TBXT) gene but is predicted to be nonfunctional and does not encode a functional protein. The functional gene, T (brachyury), is a T-box family transcription factor essential for embryonic development, particularly mesoderm formation and notochord differentiation[1][4][5]. However, *this specific pseudogene* (ENSG00000250079) is not known to be expressed as a functional protein, has no documented biological activity, therapeutic target status, or disease association. Critical explanation (is_incorrect): - This entry describes a pseudogene, not a protein-coding gene, enzyme, transporter, or receptor. It does not produce a functional protein and therefore is not a therapeutic target. - The closely related protein-coding gene is "T-box transcription factor T" (TBXT; often just "T" or "brachyury"), which is a bona fide transcription factor with roles in embryogenesis and cancer biology[1][4][5]. - If you are interested in the *functional* brachyury protein (TBXT), that entry would be appropriate for information about a developmental transcription factor and a cancer-associated biomarker/target, but ENSG00000250079/LOC100533667 is not that gene.

Other names

LOC100533667ENSG00000250079T pseudogenebrachyury homolog pseudogene