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Target intelligence / Profile preview
T cell receptor alpha joining 61 (non-functional) (TRAJ61)
- Target
- TRAJ61
- Molecular classification
- Receptor (subunit/gene segment), Other (T cell receptor gene segment, joining region)
01
Overview
T cell receptor alpha joining 61 (TRAJ61) is a gene segment within the human T cell receptor alpha locus. It encodes a joining (J) region used in DNA recombination to generate the diversity of the alpha chain of T cell receptors. TRAJ61 is annotated as non-functional, meaning it does not encode a functional J segment and does not contribute to mature T cell receptor proteins. T cell receptors are fundamental components of the adaptive immune response, recognizing antigen-derived peptides presented by MHC molecules on antigen-presenting cells. However, as a non-functional J-region segment, TRAJ61 has no direct role in receptor function or therapeutic applications. Key point: TRAJ61 is a non-functional gene segment within the T cell receptor gene cluster, not a standalone drug target or functional receptor.
- Other names
- TRAJ61T cell receptor alpha joining 61 (non-functional)
02
Biological functions
Immune response (as part of the T cell receptor gene locus)
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