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Testis expressed transcript, Y-linked 1 (TTTY1)

Target
TTTY1
Molecular classification
Long non-coding RNA (lncRNA)
01

Overview

Testis expressed transcript, Y-linked 1 (TTTY1) is a human long non-coding RNA expressed primarily in the testis, encoded by a gene located on the Y chromosome. It is described in gene catalogs as a non-protein-coding transcript, with unclear or uncharacterized biological function. There is limited evidence linking TTTY1 to disease, although some association maps mention gonadoblastoma. There is no substantiated evidence that this is a therapeutic target, and there are no known interacting drugs or mechanisms of pharmacological action[7]. Given the above, "testis expressed transcript, Y-linked 1B" is likely a misnamed or poorly defined target, and cannot be reliably connected to a meaningful therapeutic context at this time.

Other names
TTTY1Testis-specific transcript, Y-linked 1 (rare alternative)Testis expressed transcript, Y-linked, member 1
02

Biological functions

Putative regulation of spermatogenesisPossible involvement in testis-specific gene expression
03

Disease associations

Gonadoblastoma (reported association based on genomic mapping studies, functional relationship is poorly defined)

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