Testis expressed transcript, Y-linked 2B (TTTY2B)

Testis expressed transcript, Y-linked 2B (TTTY2B) is a long non-coding RNA gene located on the human Y chromosome and is predominantly expressed in testicular tissue, especially in male germline stem cells[1][2][6][7]. This gene does not code for a protein but is classified as a testis-specific transcript[2][6][7]. The broader TTTY2 gene family, which includes TTTY2B, has been implicated in male reproductive biology, and deletions have been studied for possible links to male infertility, though its exact function and disease mechanisms are not well-defined[9][5]. There are no approved drugs targeting this gene, nor is it established as a direct therapeutic target, biomarker, or source of major safety concerns[6][5].

Other names

testis-specific transcript, Y-linked 2B (non-protein coding)TTTY2B