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Target intelligence / Profile preview
Testis-specific protein Y-linked 21, pseudogene (TSPY21P)
- Target
- TSPY21P
- Molecular classification
- Other (pseudogene)
01
Overview
Testis-specific protein Y-linked 21, pseudogene (TSPY21P) is a nonfunctional DNA segment on the human Y chromosome that shares sequence similarity to the functional TSPY gene, which is important in spermatogenesis and has been implicated as a cancer-testis antigen[2][6]. Pseudogenes like TSPY21P have lost their protein-coding ability through mutation and do not participate in known biological processes or disease pathways. While the functional TSPY gene is involved in cell cycle regulation and oncogenic processes, TSPY21P does not encode for any protein and is not a recognized drug target or biomarker[1][2][6].
- Other names
- TSPY21Ptestis-specific protein Y-linked pseudogene 21member of the TSPY family of pseudogenes
02
Mechanism of action
None, since it does not produce a functional protein
03
Biological functions
None (does not encode a functional protein or exert a biological function)
04
Disease associations
None explicitly documented for TSPY21P. The functional TSPY gene is implicated in cancer, but this does not apply to its pseudogene variants
05
Safety considerations
None documented
06
Interacting drugs
None known or reported. No evidence for pharmacological or direct molecular interactions
07
Biomarkers
None specific to TSPY21P. Functional TSPY expression (not the pseudogene) may be explored as a biomarker in cancer-testis antigen studies
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