TP53 target 3 family member G, pseudogene (TP53TG3GP)

TP53 target 3 family member G, pseudogene (TP53TG3GP), is a processed pseudogene listed in the human gene catalog. Pseudogenes such as TP53TG3GP arise from gene duplication or retrotransposition and typically do not encode functional proteins. TP53TG3GP belongs to a family of pseudogenes related to TP53, a well-known tumor suppressor gene, but unlike its protein-coding relatives, TP53TG3GP is neither expressed nor functional as a receptor, enzyme, or any other drug target. Its designation as a pseudogene means it does not participate in signal transduction, cell cycle regulation, or apoptosis nor is it a target for therapeutics, clinical biomarkers, or disease modulation. TP53TG3GP and closely related pseudogenes are sometimes identified in genomic analyses, but they are not active molecular targets and should not be confused with the canonical TP53 (p53), which is a major tumor suppressor and drug target. No evidence supports TP53TG3GP as a therapeutic target, and its mention in gene or protein databases primarily serves cataloging and evolutionary research purposes.

Other names

TP53TG3GPTP53 target 3 family member G, processed pseudogene

None (no established drug mechanism of action involving this pseudogene)