TSR1, 20S rRNA accumulation, homolog pseudogene (null)

TSR1, 20S rRNA accumulation, homolog pseudogene (LOC100288510, ENSG00000248586) is classified as a pseudogene in human genomic databases. Unlike its functional counterpart (TSR1 ribosome maturation factor, ENSG00000167721), this pseudogene does not produce a protein and has no established biological activity, therapeutic role, or disease association. It is noted as homologous to yeast TSR1, but in humans, it represents a non-functioning remnant, often used only as a genomic marker rather than an actionable biological target[2]. Essential clarification: If you intended to target the *functional* TSR1 protein ("TSR1 ribosome maturation factor," involved in ribosome biogenesis and rRNA processing), refer instead to gene ENSG00000167721, not ENSG00000248586[1][5]. The sequence ENSG00000248586/LOC100288510 is strictly a pseudogene and should not be listed as a therapeutic target.

Other names

LOC100288510ENSG00000248586

null