U6 small nuclear RNA 142, pseudogene (RNU6-142P)

**RNU6-142P** refers to a *pseudogene* of U6 small nuclear RNA (snRNA). The canonical U6 snRNA is a highly conserved, abundant noncoding RNA component of the spliceosome, playing a critical role in pre-mRNA splicing by assembling at the heart of the spliceosome’s active site and coordinating the chemistry of intron removal[1][2]. However, pseudogenes such as RNU6-142P are nonfunctional genomic DNA sequences that resemble functional snRNA genes but are generally not transcribed or, if transcribed, do not participate in the canonical spliceosomal activity[3]. These pseudogenes may arise through genome duplication or retrotransposition events over evolutionary time, and while they sometimes play regulatory regulatory roles, most have no known biological function[3]. RNU6-142P is therefore not considered a therapeutic target, a receptor, or an enzyme.\n\n**Key context:**\n- The **U6 snRNA** is essential for splicing, but this entry refers specifically to a *pseudogene*, meaning it is a nonfunctional copy[1][2][3].\n- There is no evidence that **RNU6-142P** acts as a receptor, enzyme, transporter, or any other classical drug target class.\n- The molecule is generally not part of any disease mechanism, is not a biomarker, and is not targeted by any drugs.\n- Pseudogenes like RNU6-142P may serve as genetic markers in some genomic studies but do not have established roles in human biology or therapeutics[3].\n\nIf you require information on the active, functional U6 snRNA (not a pseudogene), please clarify.

Other names

RNU6-142PRNA, U6 small nuclear 142, pseudogeneU6 snRNA pseudogene 142