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U6 small nuclear RNA 198, pseudogene (RNU6-198P)

Target: RNU6-198P
Molecular classification: Other (Pseudogene), Non-coding RNA (by sequence similarity, not by function)

Overview

RNU6-198P is a genomic pseudogene resembling the U6 small nuclear RNA, annotated as the 198th variant in humans. Pseudogenes are non-functional DNA sequences that originate from duplicated or mutated active genes; while their sequence resembles functional RNA genes, they do not produce active RNA molecules. The canonical U6 snRNA is an essential non-coding RNA component of the spliceosome, responsible for intron excision during pre-mRNA splicing[1][2]. However, RNU6-198P itself does not encode a functional RNA and has no known biological or disease role[3].

Other names: RNU6-198PU6 snRNA pseudogene 198

Mechanism of action

None applicable.

Biological functions

None. Pseudogenes generally lack biological function; they are genomic relics of once-active genes and do not contribute to cellular mechanisms[3].U6 snRNA itself is involved in splicing, but pseudogenes are functionally inactive[1][2].

Disease associations

None. There is no evidence that RNU6-198P plays a role in disease[3].The functional U6 snRNA is essential for splicing, but the pseudogene variant is not implicated in pathology[1][2].

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