U6 small nuclear RNA 618, pseudogene (RNU6-618P)

U6 small nuclear RNA 618, pseudogene (RNU6-618P), is a pseudogene related to U6 small nuclear RNA (snRNA), a highly conserved non-coding RNA involved in the spliceosome complex responsible for pre-mRNA splicing in eukaryotes[1][3]. As a pseudogene, RNU6-618P is a genomic sequence resembling the functional U6 snRNA gene, but it has acquired disabling mutations or deletions that prevent it from producing a functional RNA product[2]. Pseudogenes like RNU6-618P are typically considered non-functional remnants of their parent genes, although some pseudogenes may exhibit low or tissue-specific transcriptional activity and could theoretically play regulatory roles, such as competing for regulatory factors, but there is no evidence for this specific pseudogene having such activity[2]. RNU6-618P does not encode a protein or functional RNA and is not a druggable target or therapeutic receptor/enzyme/transporter.

Other names

RNU6-618PRNA, U6 small nuclear 618, pseudogene