Ubiquitin specific peptidase 17-like family member 9, pseudogene (USP17L9P)

Ubiquitin specific peptidase 17-like family member 9, pseudogene (USP17L9P) is classified as a **pseudogene** in the human genome. Pseudogenes are genomic DNA sequences similar to normal genes but generally non-functional; they may arise from gene duplication or retrotransposition events. USP17L9P is related at the sequence level to the USP17 family, whose functional members encode enzymes called **deubiquitinating enzymes (DUBs)**, which are involved in processing ubiquitin precursors and ubiquitinated proteins, regulating processes such as protein degradation, cell signaling, and cell cycle. However, as a pseudogene, USP17L9P does not produce an active protein and is not considered a therapeutic target, biomarker, or direct participant in disease. Its related functional paralogs (i.e., USP17, not USP17L9P) control cell motility, cell cycle progression, and viability, but these activities do not apply to USP17L9P itself[3][11]. **Analysis/Notes:** - USP17L9P is a pseudogene and thus is not an active enzyme or therapeutic target[3][9][11]. - Many aliases derive from functional proteins of the USP17 family, but USP17L9P itself is not confirmed to code for a functional protein. - Resources sometimes list USP17L9P in the context of the functional USP17 family, but all Ensembl and NCBI gene databases designate it a pseudogene[3][9][11]. If you require information on the functional USP17 enzyme (not the pseudogene), please specify, as much of the literature concerns the enzyme rather than the pseudogene.

Other names

RS447USP17USP17AUSP17HUSP17IUSP17JUSP17KUSP17LUSP17Mdeubiquitinating enzyme 17ubiquitin carboxyl-terminal hydrolase 17ubiquitin specific protease 17ubiquitin thioesterase 17ubiquitin thiolesterase 17ubiquitin-specific-processing protease 17