UDP glucuronosyltransferase 2 family, polypeptide A3 pseudogene

This gene is annotated as a pseudogene within the UDP-glucuronosyltransferase 2 family and named "polypeptide A3 pseudogene." Pseudogenes are segments of DNA that resemble functional genes but typically do not encode functional proteins. There is no evidence that ENSG00000251691 expresses an active enzyme, and thus it is not involved in drug metabolism, detoxification, or other biological functions associated with active UGT enzymes[5][7]. It is not considered a therapeutic or pharmacological target. The canonical active family members (e.g., UGT2A3, UGT2A1, UGT2A2) participate in metabolism and detoxification, but pseudogenes such as this one are by definition non-functional[3][4][5]. If you are seeking a molecular target for drug metabolism or pharmacogenomics, UGT2A3 (not the pseudogene) or other functional UGTs would be relevant[3][4][6]. Key conventions followed: - Full standardized name provided - Pseudogene status clarified - Abbreviation not attached due to lack of canonical form - Aliases returned only if widely used - Families, functions, roles, interacting drugs, mechanisms, and biomarkers marked null due to pseudogene, not protein-coding status

Other names

LOC100422022UGT2A3PUGT2A3 pseudogene