Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Urinary alkalinization is a therapeutic strategy aimed at increasing urinary pH, typically to prevent or treat certain types of kidney stones, enhance drug excretion, or manage specific poisonings. It involves manipulating the acid-base balance in the urine to increase the solubility of weak acids, preventing their crystallization and promoting their elimination. This is achieved through dietary modifications or the administration of alkalizing agents such as potassium citrate or sodium bicarbonate. Monitoring urinary pH is crucial to ensure the target range is achieved and maintained, avoiding the risks of over-alkalinization.
Increases urinary pH, enhancing the solubility and excretion of certain compounds, particularly weak acids like uric acid. Shifts the equilibrium of acid-base reactions in the urine, reducing the concentration of unionized acids, which are more prone to crystallize.
2 more in the full profile.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Explore the programs pursuing this target and their development progress.
Follow the clinical studies evaluating therapies directed at this target.
Compare approaches across drug candidates, modalities, and indications.
Investigate the research and source evidence behind target biology and development.
Explore patent activity around therapies and technologies addressing this target.
Connect target biology, drug development, and emerging evidence in your research.
See how Gosset can support your research on Urinary pH (Alkalinization) (N/A).