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Vascular Endothelial Growth Factor, Fibroblast Growth Factor 1, and Fibroblast Growth Factor 2

01

Overview

This entry incorrectly groups three distinct molecular entities: Vascular Endothelial Growth Factor A (VEGF-A), Fibroblast Growth Factor 1 (FGF1), and Fibroblast Growth Factor 2 (FGF2). Each of these is a separate and canonical therapeutic target with unique properties, aliases, and drug interactions, and should be catalogued individually rather than as a single combined target. While VEGF-A and FGF2 can act synergistically in biological processes like angiogenesis, they are distinct molecular entities with separate mechanisms and are not considered a single drug target. Therapeutic interventions typically target these molecules individually or specific pathways they activate, not this generalized grouping.

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