Target intelligence / Profile preview

WDR11 antisense RNA 1 (non-protein coding) (WDR11-AS1)

Target
WDR11-AS1
Molecular classification
Other (lncRNA; long non-coding RNA)
01

Overview

WDR11 antisense RNA 1 (WDR11-AS1, also referred to as WDR11 divergent transcript or WDR11-DT) is a long non-coding RNA located opposite the protein-coding WDR11 gene on chromosome 10. Its molecular function is not well-characterized. Antisense RNAs typically act to regulate the transcription or stability of the corresponding sense gene (here, WDR11), which is implicated in developmental processes, puberty, ciliogenesis, and certain syndromic diseases. However, there is no published evidence that WDR11-DT itself acts as a therapeutic target, biomarker, or that it is involved in drug interactions or mechanisms of action. It is primarily classified as an lncRNA, with potential regulatory roles, and further research would be needed to clarify its biological significance beyond genome annotation. Notes on correctness: If the query was aiming for WDR11 protein or receptor, WDR11-DT does not encode a protein and is not a receptor, enzyme, transcription factor, or classical therapeutic target. WDR11-DT is a non-coding RNA, and current scientific literature does not support its role as a direct target in disease or therapy. The actual protein-coding gene WDR11 has associations with developmental disorders and signaling pathways—not WDR11-DT.

Other names
WDR11-DTWDR11 divergent transcriptWDR11-AS1WDR11 antisense RNA 1 (non-protein coding)
02

Biological functions

Other (Biological function is not well characterized. Antisense lncRNAs often regulate neighboring protein-coding genes, potentially affecting transcription, splicing, or epigenetics. Specific function for WDR11-DT is not well established.)
03

Disease associations

Other (No direct link to specific major diseases found. By proximity to WDR11, it may be tangentially involved in neurodevelopment or reproductive disorders if it regulates WDR11, but evidence is lacking.)

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