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XRCC1 N-terminal domain containing 1, N-terminal like (XNDC1N)

Target
XNDC1N
Molecular classification
Other
01

Overview

XRCC1 N-terminal domain containing 1, N-terminal like (XNDC1N) is a predicted protein encoded by the XNDC1N gene in humans. It is thought to enable damaged DNA binding activity and participate in single strand DNA break repair, but direct evidence of protein function, clinical significance, or targeting by drugs is lacking. The gene is localized to the nucleolus and chromosome and has no established role as a therapeutic target, receptor, enzyme, or drug interaction partner. Several aliases exist, and annotations indicate similarity to DNA repair proteins, but no well-characterized physiological or pathological associations have been described in the current scientific literature[1][2][4][5][6][7]. The gene/protein is poorly characterized and not established as a therapeutic target. No drugs or biomarker associations are reported, and its mechanism and pathogenic roles are limited to predictions, not experimentally validated functions[1][2][6][7]. Is_incorrect is set to true because this is not currently considered a clear or validated therapeutic target, and there is limited or no evidence supporting its role in disease or druggability[1][2][7].

Other names
Protein XNDC1NXRCC1 N-terminal domain-containing 1 N-terminal likeXRCC1 N-terminal domain containing 1-like proteinTrpC2-like proteinputative short transient receptor potential channel 2-like protein
02

Biological functions

Damaged DNA bindingSingle strand break repair

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