Zinc finger, FYVE domain containing 9 pseudogene (ZFYVE9P)

The zinc finger, FYVE domain containing 9 pseudogene (ENSG00000260844) is a non-protein-coding DNA sequence in the human genome classified as a pseudogene of the ZFYVE9 gene. Pseudogenes are generally remnants of once-functional genes; they usually do not yield functional proteins, are not targets for drug development, and are not biologically active except in rare regulatory or noncoding RNA contexts. In this case, there is no available evidence for biological activity for the ENSG00000260844 pseudogene; its functional paralog ZFYVE9 encodes SARA (SMAD anchor for receptor activation), which is crucial in TGF-beta signaling, but the pseudogene itself is neither a receptor, nor an enzyme, nor involved in canonical signaling pathways. Key Notes: - There is potential for confusion with the functional gene ZFYVE9, which is involved in important cellular signaling pathways and disease, but ENSG00000260844 itself is a pseudogene and does not share those characteristics. - No drugs, mechanisms, disease roles, or safety risks are associated with this pseudogene. - If a therapeutic target is needed, refer to Zinc finger FYVE domain-containing protein 9 (SARA; ZFYVE9), not the pseudogene ENSG00000260844. In summary: ENSG00000260844 refers to a non-coding pseudogene with no direct biological or therapeutic relevance; this is not an actionable drug target, but a genomic remnant related to Zinc finger FYVE domain-containing protein 9 (ZFYVE9/SARA).

Other names

Zinc finger, FYVE domain containing 9 pseudogene 1 (ZFYVE9P1)Zinc finger, FYVE domain containing 9 pseudogene 2 (ZFYVE9P2)ZFYVE9 pseudogeneENSG00000260844