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Heduo Biotech is a clinical-stage biotechnology company based in Shanghai, China, specializing in the development of oral recombinant microbial therapies. The company utilizes its proprietary engineered bacteria platform to transform probiotics into living factories that produce therapeutic proteins or enzymes directly within the intestinal tract. Their lead program, HD001, is an engineered bacterium designed to treat Phenylketonuria (PKU) by degrading phenylalanine in the gut, offering a potential oral alternative to lifelong dietary restrictions or injections. Heduo Biotech's innovative approach focuses on addressing unmet needs in metabolic and autoimmune disorders through the modulation of the gut environment.
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