11Stream

11Stream is a biotechnology company specializing in the development of advanced lipid nanoparticle (LNP) delivery systems for nucleic acid therapeutics. The company utilizes a proprietary high-throughput microfluidic platform to rapidly screen and optimize LNP formulations for specific tissue targeting and enhanced therapeutic efficacy. By streamlining the discovery process, 11Stream aims to overcome current barriers in genomic medicine delivery, particularly for extrahepatic applications. Their technology is designed to support a wide range of modalities, including mRNA, siRNA, and CRISPR-based therapies. The company is a spin-out from the University of Pennsylvania, leveraging research from the Mitchell Lab to provide targeted delivery solutions for oncology, infectious diseases, and rare genetic disorders.