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1Globe Biomedical

Beijing, Beijing Shi, Chinacn.kompass.com ↗

Ownership: Private
Development stage: Other

Overview

The company has advanced small molecule and gene-targeting therapies for oncology and metabolic diseases. Its lead program, napabucasin, is in Phase 3 for metastatic colorectal carcinoma. Other assets include GH509 in Phase 2 for nonalcoholic steatohepatitis. Several programs have been discontinued or are at earlier stages. The company leverages proprietary platforms such as gene-silencing aiRNA, synthetic biology, and nanoparticle delivery technologies to develop first-in-class therapeutics targeting cancer stem cells and metabolic disorders.

Therapeutic areas: GastroenterologyOncology
Modalities: Small moleculeDNA drugRNA drugNanoparticle (RNA drug nanomaterial delivery technology)Synthetic biology treatment
Industry: Biotech

Partnerships

Previously with International Sumitomo Pharmaceutical Group/Dainippon Sumitomo Pharma for pipeline assets like BBI608/napabucasin.

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