3Rs Collaborative

The 3Rs Collaborative (3RSC) is a non-profit organization dedicated to advancing the 3Rs—Replacement, Reduction, and Refinement—within the life sciences and animal research sectors. The organization serves as a collaborative hub, bringing together stakeholders from pharmaceutical companies, contract research organizations, academia, and regulatory agencies to implement evidence-based animal welfare practices. Their primary initiatives include the promotion of microphysiological systems (MPS), refined rodent handling, and the adoption of non-animal technologies. By providing educational resources, certification programs, and a platform for data sharing, 3RSC aims to improve both animal well-being and the translatability of scientific research. The collaborative's work is supported by a diverse membership of industry leaders committed to ethical and efficient research methodologies.