Company intelligence / Profile preview
AbilityPharma
Cerdanyola del Vallès / Barcelona area, Catalonia, Spainabilitypharma.com ↗
- Ownership
- Private
- Employees
- ~50
- Development stage
- Phase 2
01
Overview
ABTL0812 has shown positive results as first-line therapy in endometrial and squamous NSCLC when combined with standard chemotherapy. In pancreatic cancer, a double-blind placebo-controlled phase 2b trial has completed recruitment across multiple countries. The drug induces cytotoxic autophagy selectively in tumor cells via dual action on ER-stress and Akt/mTOR blockade. It also shows immunomodulatory effects. Orphan Drug Designation granted for several indications by FDA/EMA. In lung cancer trials, patient survival doubled compared to historical controls.
- Therapeutic areas
- Oncology
- Modalities
- Small molecules (oral anticancer compounds inducing autophagy)
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
SciClone Pharmaceuticals — license agreement for Greater China development/commercialization of ABTL0812.
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