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Ablaze Pharmaceuticals

Shanghai, Shanghai, Chinaprnewswire.com ↗

Ownership: Private
Employees: ~50
Development stage: Phase 3

Overview

Ablaze has established a pipeline of advanced targeted radiopharmaceutical therapies focused on oncology indications with significant unmet need in China. Its lead GPC3-targeted candidate for liver cancer has shown potent preclinical efficacy. The company also collaborates on PSMA-targeting programs and has initiated at least one Phase 3 trial for neuroendocrine tumors. Clinical results are not yet published but preclinical data indicate strong target engagement and anti-tumor activity

Therapeutic areas: Oncology
Modalities: Targeted radiopharmaceutical therapies (TRT)including peptide-based radiotherapeutics and large molecules such as Actinium-225–labeled agents
Industry: Biotech

Drug pipeline

3 assets

RYZ101

Phase 3

Indications: Gastroenteropancreatic neuroendocrine tumors, Small cell lung cancer

2 more assets in the full pipeline.

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Partnerships

RayzeBio Inc.: Exclusive development/commercial rights to several products in Greater China region.Yonghe Pharmaceutical Technology Co., Ltd.: CDMO partner for process development and cGMP manufacturing services.Eckert & Ziegler as a supplier of Lutetium‑177 radioisotope for clinical trials

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